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Transforming Cancer Care

Drug Development

Nature

Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results

Annals of Oncology

Weight Gain in Cancer Patients Treated with Brain Penetrant RET-selective Inhibitors

Nature Medicine

Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results

Investigational New Drugs

A dose escalation/expansion study evaluating dose, safety, and efficacy of the novel tyrosine kinase inhibitor surufatinib, which inhibits VEGFR 1, 2, & 3, FGFR 1, and CSF1R, in US patients with neuroendocrine tumors

Nature

In situ tumour arrays reveal early environmental control of cancer immunity

Investigational New Drugs

A phase Ib study of adavosertib, a selective Wee1 inhibitor, in patients with locally advanced or metastatic solid tumors