Genetic Testing for Cancer Risk
Cancer risk is not the same for everyone, and for some individuals and families, inherited genetic factors can play a significant role. At SCRI Oncology Partners, we recognize that genetic evaluation is an essential component of comprehensive cancer care.
We don’t just treat cancer. We assess and manage risk.
Approximately 10% of cancers are associated with inherited genetic changes. For these people, identifying hereditary cancer risk can help guide prevention, screening, and care decisions, both now and in the future. The SCRI Oncology Partners Heredity Risk Evaluation and Testing Program is designed to help individuals and their families, both in and outside of the Nashville area, better understand their inherited cancer risk and make informed health decisions.
What Is Genetic Testing?
Genes are instructions inside your body that tell cells how to grow and work. Sometimes, changes called mutations can occur in these genes. While many mutations develop naturally over time, some are inherited, meaning you are born with them. Genetic testing looks at your genes to identify any inherited mutations or abnormalities in genes that were passed on to you at birth that may increase your risk of developing certain types of cancers, including blood cancers. It is typically performed using a small blood or saliva sample.
Some cancers are more commonly associated with inherited genetic risk, including:
- Breast cancer
- Ovarian cancer
- Endometrial cancer
- Prostate cancer
- Colorectal cancer
- Pancreatic cancer
- MDS and AML
Understanding whether an inherited mutation is present allows care teams to tailor recommendations based on your individual risk profile.
Why Genetic Testing Matters
Genetic testing can be a powerful tool for informed decision-making. By better understanding your inherited cancer risk, you and your physician can develop a plan that may include earlier or more frequent screenings, prevention strategies, or personalized treatment approaches if cancer is diagnosed.
Test results can also provide important information for your family members, indicating who may share similar risks and who might also be good candidates for testing. With this knowledge, families can take a more proactive role in their health.
About Our Program
The SCRI Oncology Partners Heredity Risk Evaluation and Testing Program offers a structured genetic risk assessment for individuals who have a significant personal or family history of cancer. Our goal is to integrate genetic insights into your care in a practical, clear, and supportive way.
We work closely with both patients and referring providers throughout the process:
Step 1: Counseling Session
You’ll meet with a genetics-trained provider who will:
- Review your personal medical history
- Discuss your family’s cancer history
- Assess your likelihood of hereditary cancer risk
- Determine whether testing is appropriate
- Provide personalized screening and prevention recommendations
Step 2: Genetic Testing
If testing is recommended and you choose to proceed:
- A blood sample is collected and sent to an accredited lab
- Results are typically available within 2-3 weeks
Step 3: Results Consultation
Once results are ready, we’ll review them with you in detail:
- Clear interpretation of your results
- Personalized cancer screening recommendations
- Prevention or risk-reduction strategies
- Guidance for family members who may also benefit from testing
Expert-Led Care in Nashville
Denise A. Yardley, MD, GCRA, leads the SCRI Oncology Partners Hereditary Cancer Risk Evaluation and Testing Program. She is a recognized expert in oncology and genetic risk evaluation. Under her leadership, SCRI Oncology Partners offers a comprehensive and compassionate approach to hereditary cancer risk assessment.
Is Genetic Testing Right for You?
Many people consider genetic testing because of their own or their family’s medical history, or when they have limited information about their biological family’s cancer history. You may consider genetic testing if your personal or family history includes:
- Cancer diagnosed in multiple generations
- Multiple cancers in one family member
- Cancer diagnosed before age 50
- A known gene mutation in the family
- Certain rare or uncommon cancer patterns
- Family or personal history of MDS or AML
Genetic testing is often covered by health insurance, and financial assistance may be available if needed. Patients sometimes worry about how genetic information can be used. Federal and state laws help prevent discrimination by health insurers and employers based on genetic test results.
At SCRI OncologyPartners, genetic risk assessment and evaluation begin with a careful review of your personal and family history. Our team will help determine whether genetic testing may be appropriate for you and ensure you understand the potential benefits and limitations before moving forward.
Take the Next Step in Understanding Your Cancer Risk
Understanding your cancer risk can help shape a healthier future for you and your family. If you think you may be at risk for hereditary cancer, we’re here to help you find answers. Review this checklist. It will help you and your doctor determine if genetic counseling and testing may be right for you.
If you feel you’re a good candidate for genetic counseling, request an appointment with Dr. Yardley, located at our cancer center in Nashville.
We’re here when you need us
If you were recently diagnosed or would like a second opinion, request an appointment with one of our experienced cancer doctors right here in Nashville.
We’re here when you need us
If you were recently diagnosed or would like a second opinion, request an appointment with one of our experienced cancer doctors right here in Nashville.
We’re here when you need us
If you were recently diagnosed or would like a second opinion, request an appointment with one of our experienced cancer doctors right here in Nashville.